Pilot-scale process development for recombinant adeno-associated virus (rAAV) production based on high-density Sf9 cell culture
This successful experiment not only provides a technological basis for further scale-up but also guarantees product capacity. We hope that this development process can provide reference data for studying cell culture-based drug production.
Authors
- Jieyi Gu
- Xinran Li (ORCID: https://orcid.org/0000-0001-8988-7223)
- Haoquan Wu
- Yuanyuan Xie (ORCID: https://orcid.org/0000-0001-5374-0094)
Institutions
- Kaneka (United States) (US)
- Hangzhou DAC Biotech (China) (CN)
- Zhejiang University of Technology (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s12985-024-02550-4
- Citations
- 2
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.10