Perioperative Observations and Outcome in Surgical Treatment of Malignant Peripheral Nerve Sheath Tumors

NF1-associated MPNSTs have larger tumor volumes, higher SUVs and MIB-1 proliferation indices, and a shorter overall survival period. Nevertheless, surgery can improve symptoms, particularly medication-resistant pain, and should also be considered in advanced disease for symptom control/improvement.

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Publication Details

Journal
Cancers
Published
2024-11-07
DOI
https://doi.org/10.3390/cancers16223757
Citations
2
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.74

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article

Perioperative Observations and Outcome in Surgical Treatment of Malignant Peripheral Nerve Sheath Tumors

Isabel Gugel, Martin U. Schuhmann, Helmut Dittmann, Julian Zipfel et al.
2 citations
Cancers
Neurofibromatosis and Schwannoma Cases
0.74
article

Perioperative Observations and Outcome in Surgical Treatment of Malignant Peripheral Nerve Sheath Tumors

Isabel Gugel, Martin U. Schuhmann, Helmut Dittmann, Julian Zipfel, Konstantin Nikolaou, Ruth Ladurner, Marcos Soares Tatagiba, Benjamin Bender, Jonas Tellermann, Kevin Paul Ferraris, Volker Steger, Florian Grimm, Antje Bornemann, Jürgen Schäfer
article en
2 citations

Abstract

NF1-associated MPNSTs have larger tumor volumes, higher SUVs and MIB-1 proliferation indices, and a shorter overall survival period. Nevertheless, surgery can improve symptoms, particularly medication-resistant pain, and should also be considered in advanced disease for symptom control/improvement.

CancersVol. 16(22)
University of British Columbia (CA), University Children's Hospital Tübingen (DE), BC Children's Hospital (CA), University of Tübingen (DE)
Brandenburger Staatsministerium für Wissenschaft, Forschung und Kultur
Good health and well-being
Openalex Percentile: Top 26%
Neurofibromatosis and Schwannoma Cases
0.74
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