m <sup>6</sup> A Modification of Profilin-1 in Vascular Smooth Muscle Cells Drives Phenotype Switching and Neointimal Hyperplasia via Activation of the p-ANXA2/STAT3 Pathway
This study unveils the significance of PFN1 N<sup>6</sup>-methyladenosine modification in VSMCs, demonstrating its role in promoting phenotype switching and neointimal hyperplasia through the activation of the p-ANXA2 (phospho-ANXA2)/STAT3 pathway.
Authors
- Haoyue Tang (ORCID: https://orcid.org/0009-0008-0632-8222)
- Zhen Ge (ORCID: https://orcid.org/0000-0003-0423-3664)
- Ai‐Qun Chen (ORCID: https://orcid.org/0000-0002-0933-7406)
- Xiangquan Kong
- Wenying Zhou (ORCID: https://orcid.org/0000-0002-9249-8939)
- Junjie Zhang (ORCID: https://orcid.org/0000-0003-2710-8516)
- Huan Zhang (ORCID: https://orcid.org/0009-0009-1420-0154)
- Feng Wang (ORCID: https://orcid.org/0000-0003-2771-5543)
- Yue Gu (ORCID: https://orcid.org/0000-0002-6633-675X)
- Liguo Wang (ORCID: https://orcid.org/0000-0003-2072-4826)
- Shao‐Liang Chen (ORCID: https://orcid.org/0000-0002-3887-952X)
- Zhimei Wang (ORCID: https://orcid.org/0000-0002-0942-8287)
- Xiaofei Gao (ORCID: https://orcid.org/0000-0001-7428-119X)
- Wei Lu (ORCID: https://orcid.org/0000-0001-6614-8727)
- Guo‐Ying Zuo
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1161/atvbaha.124.321399
- Citations
- 14
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.27