Uncovering Molecular and Genetic Drivers of Dental Caries Via scRNA-seq and Mendelian Randomisation
By combining scRNA-seq with MR, this study provides a comprehensive molecular and genetic framework for understanding dental caries. Our findings suggest that targeting these pathways could enhance prevention and treatment strategies, paving the way for precision medicine in dental care. Future research should explore these genes' functional roles in caries progression and their potential as biomarkers for early detection and therapeutic targeting.
Authors
- Chao Guo (ORCID: https://orcid.org/0000-0002-2581-4487)
- Yu Zhou (ORCID: https://orcid.org/0000-0001-5999-7966)
- Jian Wang (ORCID: https://orcid.org/0000-0002-0788-6604)
- Zhiwei Li (ORCID: https://orcid.org/0009-0006-2550-7686)
- William Xu
- Qinjiang Bian
Institutions
- Shihezi University (CN)
- Hubei University of Medicine (CN)
- Gansu Provincial Hospital (CN)
- First Affiliated Hospital of Shihezi University Medical College (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1016/j.identj.2024.10.005
- Citations
- 2
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Hubei University of Medicine
- Hubei University