Intra-articular Vancomycin Reduces Prosthetic Infection in Primary Hip and Knee Arthroplasty—Response to Queries

We thank the authors for taking the time to thoroughly read our paper entitled “Intra-articular Vancomycin Reduces Prosthetic Infection in Primary Hip and Knee Arthroplasty” and giving us the opportunity to clarify some of the points you raised. To your first point, all patients had 2 g IV cefazolin. The Australian Surgical Antibiotic Prosphylaxis trial which combined vancomycin and cefazolin surgical antibiotic prophylaxis in arthroplasty finished recruitment prior to this study [1] and the results were unpublished at the time of our study development.