Prevalence of Transthyretin Cardiac Amyloidosis in Undifferentiated Heart Failure with Preserved Ejection Fraction
In an undifferentiated HFpEF cohort, 8% were found to have wild-type ATTR-CM using a DPD scintigraphy-based screening protocol. Screening undifferentiated HFpEF patients is associated with a significant diagnostic yield, which can be further increased by targeting older males with increased LV wall thickness and elevated high-sensitivity troponin levels.
Authors
- Eoin C. Kavanagh (ORCID: https://orcid.org/0000-0001-5933-5700)
- Alasdair Gray (ORCID: https://orcid.org/0000-0003-1460-8327)
- D. O'Sullivan
- Laura Murphy (ORCID: https://orcid.org/0000-0002-7409-931X)
- Niall Mahon (ORCID: https://orcid.org/0000-0002-2872-2297)
- C Howley
- Emer Joyce (ORCID: https://orcid.org/0000-0002-1241-0870)
- Gerard Giblin (ORCID: https://orcid.org/0000-0002-7452-5526)
- Laura Healy (ORCID: https://orcid.org/0000-0001-5821-1853)
- Allan Clark (ORCID: https://orcid.org/0000-0003-2965-8941)
- Neasa Starr (ORCID: https://orcid.org/0000-0001-5544-7908)
- Aaron F. McDaid (ORCID: https://orcid.org/0000-0002-5209-8869)
- Martin O’Connell (ORCID: https://orcid.org/0000-0002-0048-0716)
- James O’Neill (ORCID: https://orcid.org/0000-0002-1773-6511)
- Cecelia Tracey
- E. Morrin
Institutions
- University College Dublin (IE)
- Royal College of Surgeons in Ireland (IE)
- Mater Misericordiae University Hospital (IE)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1002/ehf2.15112
- Citations
- 10
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.34
Funders
- Pfizer