Brain Metastases in Sarcomas: A Multicenter Retrospective Cohort Study
Our findings identify that patients with metastatic sarcoma to the brain have poor prognoses, often have concurrent metastasis, and have a median survival of only 6 months. Additionally, our study found that leptomeningeal metastases is a rare presentation with poor survival outcomes. There are various treatment modalities for sarcomas with BM; however, there are no guidelines, unlike in other malignancies. Further research is necessary to evaluate the role of therapeutic measures in terms of type, timing, and outcomes.
Authors
- Nam Q. Bui (ORCID: https://orcid.org/0000-0001-6896-4349)
- Brian Andrew Van Tine (ORCID: https://orcid.org/0000-0003-4572-6668)
- Kristen N. Ganjoo (ORCID: https://orcid.org/0000-0003-0452-9967)
- Angela C. Hirbe (ORCID: https://orcid.org/0000-0003-1719-0771)
- Sheima Farag (ORCID: https://orcid.org/0000-0002-1634-5033)
- Aisha Miah (ORCID: https://orcid.org/0000-0001-6946-0820)
- Elizabeth J. Davis (ORCID: https://orcid.org/0000-0001-7626-2435)
- Hilary Dietz (ORCID: https://orcid.org/0000-0001-9586-9902)
- Vicki L. Keedy (ORCID: https://orcid.org/0000-0002-7213-7562)
- Ellen Zhang (ORCID: https://orcid.org/0000-0001-5365-4209)
- Daniel Wang (ORCID: https://orcid.org/0000-0002-9336-4123)
- Shane Zaid
Institutions
- Baylor College of Medicine (US)
- Washington University in St. Louis (US)
- Royal Marsden Hospital (GB)
- Ithaca College (US)
- Vanderbilt University Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- Cancers
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3390/cancers16223760
- Citations
- 4
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.68