ALKBH5 activates CEP55 transcription through m6A demethylation in FOXP2 mRNA and expedites cell cycle entry and EMT in ovarian cancer
ALKBH5 hinders FOXP2-mediated transcriptional repression of CEP55 to promote the malignant progression of OC via cell cycle and EMT.
Authors
- Lin Kang (ORCID: https://orcid.org/0000-0002-9186-9574)
- Xing Chen (ORCID: https://orcid.org/0000-0001-9028-5342)
- Xiaoxiao Ding (ORCID: https://orcid.org/0000-0001-7177-6007)
- Kai Wang (ORCID: https://orcid.org/0000-0003-2066-398X)
- Junhui Yu (ORCID: https://orcid.org/0000-0002-6270-7891)
- Tianxin Zhang (ORCID: https://orcid.org/0000-0001-5535-2976)
Institutions
- Wenzhou Medical University (CN)
- Taizhou Central Hospital (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Biology Direct
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s13062-024-00551-5
- Citations
- 7
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents