Phase IV adaptive randomised clinical trials evaluating efficacy and cost-efficacy of pre-emptive pharmacogenetic genotyping strategies in the Spanish National Health System: iPHARMGx Master Protocol and PREVESTATGx nested clinical trial
EU CT number: 2023-509418-12-00/Clinical trial Identifier (ClinicalTrials.gov): NCT06262685. Protocol version 1.2 12 April 2024 (includes non-substantial modification number 14 June 2024). Trial registration of this study can be located at both the EU Clinical Trials Register available from https:// euclinicaltrials.eu/search-for-clinical-trials/?lang=en and https://clinicaltrials.gov. Registration on both websites was done before the enrolment of the first patient complying with European regulations. EU Clinical Trials Register is a primary registry according to the WHO.
Authors
- Montserrat Carmona (ORCID: https://orcid.org/0000-0002-4680-7745)
- Alberto Manuel Borobia (ORCID: https://orcid.org/0000-0002-8584-3263)
- Francisco Abad‐Santos (ORCID: https://orcid.org/0000-0002-6519-8885)
- Rocío Rosas-Alonso (ORCID: https://orcid.org/0000-0002-3331-2161)
- María del Mar García Saiz
- Enrique Seco-Meseguer
- Elena Diago-Sempere (ORCID: https://orcid.org/0000-0002-6109-9599)
- Iñaki Imaz-Iglesia (ORCID: https://orcid.org/0000-0002-7864-4194)
- Consuelo Rodríguez‐Jiménez (ORCID: https://orcid.org/0000-0001-8940-3962)
- Ana M. Peiró (ORCID: https://orcid.org/0000-0002-2385-3749)
- Judith Sanabria‐Cabrera (ORCID: https://orcid.org/0000-0002-7769-7008)
- Magı́ Farré (ORCID: https://orcid.org/0000-0001-8338-7543)
- Miriam Estébanez (ORCID: https://orcid.org/0000-0003-4509-9123)
- Luis A. López‐Fernández
- Antonio J. Carcas (ORCID: https://orcid.org/0000-0003-1823-4174)
- Stefan Stewart (ORCID: https://orcid.org/0000-0001-7181-7235)
- Miriam Saiz‐Rodríguez (ORCID: https://orcid.org/0000-0002-1660-3135)
- Lucía Pedrosa (ORCID: https://orcid.org/0000-0002-7486-515X)
- Alicia Marín-Candón (ORCID: https://orcid.org/0000-0001-8883-3151)
- Emilio J. Laserna‐Mendieta (ORCID: https://orcid.org/0000-0002-9039-7667)
- Irene García-García (ORCID: https://orcid.org/0000-0002-4831-9374)
Institutions
- Universitat Autònoma de Barcelona (ES)
- Hospital Universitario de Canarias (ES)
- Hospital Universitario La Paz (ES)
- Instituto de Salud Carlos III (ES)
- Generalitat Valenciana (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Marqués de Valdecilla University Hospital (ES)
- Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES)
- Spanish Clinical Research Network (ES)
- Hospital General de Tomelloso (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Universitario de Burgos (ES)
- Hospital Universitario de La Princesa (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
- Hospital Central de la Defensa Gómez Ulla (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- Agencia de Evaluación de Tecnologías Sanitarias (ES)
- Universidad Autónoma de Madrid (ES)
- University of Castilla-La Mancha (ES)
- Universidad de Málaga (ES)
Publication Details
- Journal
- BMJ Open
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-089823
- Primary Topic
- Pharmaceutical studies and practices
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto de Salud Carlos III