Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma

We have developed novel patient-centred paediatric and adult CONFiRMs that include quality of life measures. CONFiRMs should allow a more holistic understanding of response for the patient and a standardised assessment of the effectiveness of biologics between studies. Further research is needed to prospectively validate CONFiRM scores.

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Publication Details

Journal
European Respiratory Journal
Published
2024-11-07
DOI
https://doi.org/10.1183/13993003.00691-2024
Citations
14
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
4.57

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article

Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma

Ramesh Kurukulaaratchy, Niels W. Rutjes, Atul Gupta, Katharina Blümchen et al.
14 citations
European Respiratory Journal
Asthma and respiratory diseases
4.57
article

Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma

Ramesh Kurukulaaratchy, Niels W. Rutjes, Atul Gupta, Katharina Blümchen, Anneke Ten Brinke, Guy Brusselle, Mariko Siyue Koh, Vera Mahler, Salman Siddiqui, Simone Hashimoto, Constance H. Katelaris, Paul Seddon, Liam Gabriel Heaney, Gerard H. Koppelman, Stephen James Fowler, Louise Fleming, Mariëlle W. Pijnenburg, Courtney Coleman, Matthias Kopp, Sejal Saglani, Katrien Eger, Jonathan Corren, Matthew Masoli, Steve Turner, Peter A. B. Wark, Susanne J. H. Vijverberg, Mika J. Mäkelä, Gunilla Hedlin, John W. Upham, Michael E. Wechsler, Kian Fan Chung, ARNAUD AB BOURDIN, Katrin Milger, Barbro Dahlén, Katharine C. Pike, Ratko Djukanović, Florian Singer, Hans Michael Haitchi, Roxana Silvia Bumbăcea, Alan Altraja, Christopher Edward Brightling, Erik Melén, Hitasha Rupani, Tomoko Tajiri, Apostolos Bossios, Alexander G. Mathioudakis, Parameswaran Nair, Ji‐Hyang Lee, Inger Kull, Erol Gaillard, Clare Murray, Andrew Bush, Graham W. Clarke, Graham Roberts, Alexander Mœller, Bulent Taner Karadag, Valentyna Yasinska, Thomas B. Casale, Anna Rattu, David J. Jackson, A. Deschildre, Rekha Chaudhuri, Monika Gappa, Ekaterina Khaleva, James Y. Paton, Philippe Bégin, Celeste Porsbjerg, Jenny Negus, Franca Rusconi, Hua Wen, Nikolaos G. Papadopoulos, Prasad Nagakumar, Antonio Nieto, Ángel Mazón, Andrew Exley, Thomas Eiwegger, Markaya Henderson
article en
14 citations

Abstract

We have developed novel patient-centred paediatric and adult CONFiRMs that include quality of life measures. CONFiRMs should allow a more holistic understanding of response for the patient and a standardised assessment of the effectiveness of biologics between studies. Further research is needed to prospectively validate CONFiRM scores.

European Respiratory JournalVol. 65(3)
Goethe University Frankfurt (DE), Ulsan College (KR), University of Bern (CH), Queen's University Belfast (GB), Camden and Campbelltown Hospitals (AU), University Medical Center Groningen (NL), Karolinska University Hospital (SE), University of Helsinki (FI), University of Leicester (GB), University of California, Los Angeles (US), Carol Davila University of Medicine and Pharmacy (RO), The University of Queensland (AU), National University of Singapore (SG), University of Groningen (NL), King's College London (GB), University of Toronto (CA), University of Aberdeen (GB), Université de Montpellier (FR), Guy's and St Thomas' NHS Foundation Trust (GB), National and Kapodistrian University of Athens (GR), Medical University of Graz (AT), Singapore General Hospital (SG), Université de Lille (FR), University of Exeter (GB), University of South Florida (US), Manchester Academic Health Science Centre (GB), Helsinki University Hospital (FI), University Hospital of Bern (CH), Ghent University Hospital (BE), Royal Devon and Exeter Hospital (GB), Hospital for Sick Children (CA), British Lung Foundation (GB), Asan Medical Center (KR), Princess Alexandra Hospital (AU), Bristol Royal Hospital for Children (GB), Bispebjerg Hospital (DK), Tartu University Hospital (EE), Centre Hospitalier Universitaire Sainte-Justine (CA), Medisch Centrum Leeuwarden (NL), University Hospital Southampton NHS Foundation Trust (GB), Royal Alexandra Children's Hospital (GB), Karolinska Institutet (SE), University of Manchester (GB), Centre Hospitalier Universitaire de Lille (FR), LMU Klinikum (DE), Hospital Universitari i Politècnic La Fe (ES), National Jewish Health (US), Nagoya City University (JP), University of Ulsan (KR), Physiologie et Médecine Expérimentale du Coeur et des Muscles (FR), Manchester University NHS Foundation Trust (GB), NHS Grampian (GB), Stockholm South General Hospital (SE), Emma Kinderziekenhuis (NL), Royal Brompton Hospital (GB), Center for Infection and Immunity of Lille (FR), Birmingham Children's Hospital (GB), Lung Institute (US), Hôpital Jeanne de Flandre (FR), St Mary's Hospital (GB), NIHR Imperial Biomedical Research Centre (GB), Universitätsklinikum St. Pölten (AT), AstraZeneca (Brazil) (BR), Media Working Group (US), NIHR Southampton Biomedical Research Centre (GB), Leitat Technological Center (ES), University Children’s Hospital Bern (CH), Evangelisches Krankenhaus Düsseldorf (DE), University Children's Hospital Zurich (CH), German Center for Lung Research (DE), European Federation of Allergy and Airways Diseases Patients Associations (BE), University Hospital Frankfurt (DE), AstraZeneca (Finland) (FI), David Hide Asthma and Allergy Research Centre (GB), Erasmus MC - Sophia Children’s Hospital (NL), Centre Hospitalier de l’Université de Montréal (CA), AstraZeneca (Sweden) (SE), Karl Landsteiner University of Health Sciences (AT), Wythenshawe Hospital (GB), Amsterdam University Medical Centers (NL), King's College Hospital (GB), Azienda Usl Toscana Centro (IT), Second Affiliated Hospital of Zhejiang University (CN), NIHR Manchester Biomedical Research Centre (GB), Hospital District of Helsinki and Uusimaa (FI), NIHR Leicester Biomedical Research Centre (GB), University of Southampton (GB), Imperial College London (GB), University of Tartu (EE), Monash University (AU), St. Joseph’s Healthcare Hamilton (CA), Western Sydney University (AU), Marmara University (TR), University of Glasgow (GB), University of Birmingham (GB), Ludwig-Maximilians-Universität München (DE), Paul Ehrlich Institut (DE), University of Amsterdam (NL), University of Colorado Denver (US), McMaster University (CA)
Amgen, Eli Lilly and Company, Pfizer, AstraZeneca, GlaxoSmithKline, Sanofi, Teva Pharmaceutical Industries, Chiesi Farmaceutici, University of Otago, European Respiratory Society, Regeneron Pharmaceuticals, Nestlé Health Science, Vertex Pharmaceuticals, Celldex Therapeutics, European Federation of Pharmaceutical Industries and Associations, Cerecor, Aimmune Therapeutics, Incyte, Celltrion, National Institute for Health and Care Research, University of Southampton, European Commission, Rijksuniversiteit Groningen, ZonMw, Universiteit van Amsterdam, Karolinska Institutet, AAIR Charity, Shionogi, Karl-Franzens-Universität Graz, Medizinische Universität Graz, Innovative Medicines Initiative, Bausch Health, National Institute for Health Research Southampton Biomedical Research Centre, Genentech, Novartis Pharma, Manchester Biomedical Research Centre, Imperial Experimental Cancer Medicine Centre, Medical Research Council, Engineering and Physical Sciences Research Council, NIHR Imperial Biomedical Research Centre, NIHR Leicester Biomedical Research Centre
Reduced inequalities
Openalex Percentile: Top 4%
Asthma and respiratory diseases
4.57
DOIOpen Access PDFOpenAlex
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