Diagnostic performance of Typhidot RDT in diagnosis of typhoid fever and antibiotic resistance characterisation in a cross-sectional study in Southern Ghana
These findings suggest sub-optimal performance of the Typhidot RDT for diagnosis of typhoid in Ghana with a higher chance for misdiagnosis and misapplication of antibiotics. The high proportion of isolates recovered from stool culture is consistent with the pathophysiology of bacterial shedding during the acute phase of infection, which provides a window of opportunity to control typhoid transmission.
Authors
- Emre Şam (ORCID: https://orcid.org/0000-0001-7706-465X)
- Samuel Duodu (ORCID: https://orcid.org/0000-0003-2791-8949)
- Kwesi Z. Tandoh (ORCID: https://orcid.org/0000-0002-1628-2845)
- Lucas Naam-Kayagre Amenga-Etego (ORCID: https://orcid.org/0000-0003-4468-0506)
- Felix Ansah (ORCID: https://orcid.org/0000-0002-6928-2363)
- Johnson Alagbo
- Avis Asamoah
Institutions
- University of Ghana (GH)
- Noguchi Memorial Institute for Medical Research (GH)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s12879-024-10160-2
- Citations
- 2
- Primary Topic
- Salmonella and Campylobacter epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Institute for Health and Care Research
- University of Ghana