Pulmonary gas exchange in relation to exercise pulmonary hypertension in patients with heart failure with preserved ejection fraction
These data suggest that EePH contributes to pulmonary gas exchange impairments during exercise by causing a ventilation/perfusion mismatch that provokes both ventilatory inefficiency and hypoxaemia, both of which seem to contribute to dyspnoea on exertion and exercise intolerance in patients with HFpEF.
Authors
- James P. MacNamara (ORCID: https://orcid.org/0000-0003-2795-6021)
- Denis J. Wakeham (ORCID: https://orcid.org/0000-0002-4200-3790)
- Benjamin D. Levine (ORCID: https://orcid.org/0000-0001-9064-7251)
- Bryce N. Balmain (ORCID: https://orcid.org/0000-0002-2642-7083)
- Satyam Sarma (ORCID: https://orcid.org/0000-0002-0628-4919)
- Josh T. Goh (ORCID: https://orcid.org/0009-0000-7937-0300)
- Tiffany Brazile
- Tony G. Babb
- Michael G. Leahy (ORCID: https://orcid.org/0000-0002-9209-3982)
- Linda S. Hynan (ORCID: https://orcid.org/0000-0002-4642-7769)
- Kevin C. Lutz (ORCID: https://orcid.org/0000-0002-6687-0637)
- Andrew R. Tomlinson (ORCID: https://orcid.org/0000-0001-9899-0812)
Institutions
- Texas Health Dallas (US)
- Institute for Exercise and Environmental Medicine (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1183/13993003.00722-2024
- Citations
- 3
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- University of Texas Southwestern Medical Center
- University of California, San Diego
- National Heart, Lung, and Blood Institute