A network of pro-inflammatory genes repressed by clock signalling in bronchial epithelium
Our results provide an unbiased and comprehensive analysis of the gene expression network coexpressed with circadian clock signalling in bronchial epithelium. Our findings suggest an association between circadian clock signalling and enhanced inflammatory gene expression in COPD patients.
Authors
- Philip J. Johnson (ORCID: https://orcid.org/0000-0002-8180-7601)
- Anika Nagelkerke (ORCID: https://orcid.org/0000-0002-7541-588X)
- Loes Kistemaker (ORCID: https://orcid.org/0000-0002-7742-8748)
- Dirk‐Jan Slebos (ORCID: https://orcid.org/0000-0001-9555-3422)
- Pallav L. Shah (ORCID: https://orcid.org/0000-0002-9052-4638)
- Karthi Srikanthan (ORCID: https://orcid.org/0000-0002-6751-5020)
- Siti Farah Rahmawati (ORCID: https://orcid.org/0000-0003-3530-1439)
- Xiaopeng Li (ORCID: https://orcid.org/0000-0003-1900-2017)
- Reinoud Gosens
Institutions
- University Medical Center Groningen (NL)
- Bandung Institute of Technology (ID)
- University of Groningen (NL)
- Royal Brompton Hospital (GB)
- Nuvaira (United States) (US)
- Dialyse Centrum Groningen (NL)
- Imperial College London (GB)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1183/23120541.00605-2024
- Citations
- 2
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.55
Funders
- Distinguished International Students Scholarship