Real-world effectiveness and safety of simnotrelvir/ritonavir for COVID-19: A nationwide, multicenter, prospective, observational cohort study in China
In real world, S/R significantly reduced the incidence of COVID-19-related hospitalization, demonstrated favorable safety profiles, and less use of combined medication.
Authors
- Yun-qing Wei
- Shuangsuo Dang (ORCID: https://orcid.org/0000-0002-8451-1072)
- Min Deng (ORCID: https://orcid.org/0000-0001-6432-3202)
- Yan Gong (ORCID: https://orcid.org/0000-0001-6644-6994)
- Gang He (ORCID: https://orcid.org/0000-0001-9806-4069)
- Wenjie Yang (ORCID: https://orcid.org/0000-0003-1993-1860)
- Tengfei Ma (ORCID: https://orcid.org/0000-0002-8916-7370)
- Rui Yuan (ORCID: https://orcid.org/0000-0002-6603-6423)
- Zhenhua Deng (ORCID: https://orcid.org/0000-0001-8585-853X)
- Zhinan Shou
- Tianxin Xiang (ORCID: https://orcid.org/0000-0002-1673-6077)
- Jing Yuan (ORCID: https://orcid.org/0000-0002-1184-7456)
- Song Xu (ORCID: https://orcid.org/0000-0002-4263-5632)
- Qingyu Zhang (ORCID: https://orcid.org/0000-0002-8742-1697)
- Zhongfa Zhang (ORCID: https://orcid.org/0009-0009-0805-8470)
- Yong Xiong (ORCID: https://orcid.org/0000-0003-0678-4064)
- Tongbai Xu
- Xiaomei Yuan (ORCID: https://orcid.org/0000-0002-8248-5405)
- Lanbing Zheng
- Chunling Du (ORCID: https://orcid.org/0000-0002-1310-682X)
- Chongjie Pang (ORCID: https://orcid.org/0000-0002-1856-9268)
- Huan Chen (ORCID: https://orcid.org/0000-0003-4125-0666)
- Jinghua Wang (ORCID: https://orcid.org/0000-0003-2198-2659)
- Libing Ma (ORCID: https://orcid.org/0000-0002-7234-2312)
- Jing Huang (ORCID: https://orcid.org/0000-0002-2167-8385)
- Hongying Liu (ORCID: https://orcid.org/0000-0003-2447-2849)
- Yunfeng Qiao
- Jikang Yang
- Ran Cao (ORCID: https://orcid.org/0000-0002-0546-7668)
- Yunfeng Wu (ORCID: https://orcid.org/0000-0002-0302-1697)
- Bing Han (ORCID: https://orcid.org/0000-0002-0688-6637)
- Jing Xu (ORCID: https://orcid.org/0000-0002-3946-2056)
- Jinghua Ma
- Jianping Dong
- Yan Huang (ORCID: https://orcid.org/0000-0002-4747-3740)
- Xiangjie Zhang (ORCID: https://orcid.org/0009-0001-8338-514X)
- Zhouchi Ni
- Jianfen Gao
- B. Gao (ORCID: https://orcid.org/0000-0003-4200-3974)
- Rongmeng Jiang
- Renhong Tang (ORCID: https://orcid.org/0009-0005-3494-707X)
- Yang Jian-kun
- Lisheng Yang
- Yu Zhong (ORCID: https://orcid.org/0000-0001-5728-871X)
Institutions
- Hebei Medical University (CN)
- Central South University (CN)
- Nanchang University (CN)
- Xinjiang Medical University (CN)
- Guilin Medical University (CN)
- Capital Medical University (CN)
- Fudan University (CN)
- Tianjin First Center Hospital (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- Tianjin Medical University General Hospital (CN)
- Wuhan University (CN)
- Beijing Shijingshan Hospital (CN)
- Jiaxing University (CN)
- Tianjin Nankai Hospital (CN)
- People 's Hospital of Jilin Province (CN)
- People’s Hospital of Rizhao (CN)
- Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital (CN)
- Community Care (US)
- Shanghai Public Health Clinical Center (CN)
- Hebei Yiling Hospital (CN)
- Hebei General Hospital (CN)
- Jiaozuo University (CN)
- Xingtai People's Hospital (CN)
- First Affiliated Hospital of Xinxiang Medical University (CN)
- Taishan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Zhongshan Hospital (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Anqing City Hospital (CN)
- First Hospital of Jiaxing (CN)
- PLA Navy General Hospital (CN)
- The First People's Hospital of Guiyang (CN)
- Community Health Center (US)
- Jiangmen Central Hospital (CN)
- Taishan Medical University (CN)
- Beijing Ditan Hospital (CN)
- Ningbo University Affiliated Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Beijing Haidian Hospital (CN)
- First People's Hospital of Chongqing (CN)
- Fu Wai Hospital (CN)
- Jinhua Central Hospital (CN)
- First Hospital of Xi'an (CN)
- First Affiliated Hospital of Nanchang University (CN)
- Fourth Hospital of Inner Mongolia (CN)
- Shenzhen Third People’s Hospital (CN)
- Tianjin Medical University (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Journal of Infection
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1016/j.jinf.2024.106339
- Citations
- 4
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- Chinese Center for Disease Control and Prevention
- Beijing Municipal Health Commission
- National Health Commission of the People's Republic of China