Hemoglobin vesicles improve neurological outcomes after cardiac arrest in rats
The administration of HbVs during resuscitation was effective in mitigating brain damage after whole-brain ischemia in rats, as demonstrated by improved histopathological and neurological outcomes. This suggests potential neurological benefits for patients during resuscitation, although further research in larger animal models is required to validate these findings.
Authors
- Keisuke Tsuruta (ORCID: https://orcid.org/0000-0001-6145-7301)
- Hidetada Fukushima (ORCID: https://orcid.org/0000-0001-8135-8626)
- Hiromi Sakai (ORCID: https://orcid.org/0000-0002-0681-3032)
Institutions
- Nara Medical University (JP)
Publication Details
- Journal
- Resuscitation Plus
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1016/j.resplu.2024.100819
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Nara Medical University
- Japan Society for the Promotion of Science