<scp>miR</scp>‐155 promotes <scp>m6A</scp> modification of <scp>SOX2 mRNA</scp> through targeted regulation of <scp>HIF</scp>‐1α and delays wound healing in diabetic foot ulcer in vitro models
Inhibition of miR-155 promoted the expression of HIF-1α and attenuated the m6A modification of SOX2 mRNA, thereby promoting the expression of SOX2 and activating the downstream EGFR/MEK/ERK signaling pathway to promote wound healing in an in vitro DFU model.
Authors
- Jiarui Peng
- Bin Ruan
- Hong Zhu (ORCID: https://orcid.org/0000-0001-5664-660X)
- Zhisheng Duan
- Mei Cao (ORCID: https://orcid.org/0000-0003-0109-0637)
Institutions
- Third People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Journal of Diabetes Investigation
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1111/jdi.14327
- Citations
- 9
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.10