Isoscopoletin inhibits hepatocellular carcinoma cell proliferation via regulating glycolysis-related proteins

This study suggests that isoscopoletin may exist an anti-tumor effect by regulating the glycolysis-related proteins GPD2, GPI, Hsp90α and PGK2, inhibiting the glycolysis process in HCC cells, then blocking the energy supply of tumor cells.

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Publication Details

Journal
PLoS ONE
Published
2024-11-07
DOI
https://doi.org/10.1371/journal.pone.0310530
Citations
1
Primary Topic
Seaweed-derived Bioactive Compounds
Type
article
Field-Weighted Citation Impact
0.60

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article

Isoscopoletin inhibits hepatocellular carcinoma cell proliferation via regulating glycolysis-related proteins

Chen Wang, Zhihui Zhu, Jiawen Gu, Changwu Ruan
1 citations
PLoS ONE
Seaweed-derived Bioactive Compounds
0.60
article

Isoscopoletin inhibits hepatocellular carcinoma cell proliferation via regulating glycolysis-related proteins

Chen Wang, Zhihui Zhu, Jiawen Gu, Changwu Ruan
article en
1 citations

Abstract

This study suggests that isoscopoletin may exist an anti-tumor effect by regulating the glycolysis-related proteins GPD2, GPI, Hsp90α and PGK2, inhibiting the glycolysis process in HCC cells, then blocking the energy supply of tumor cells.

PLoS ONEVol. 19(11)
Zhejiang Chinese Medical University (CN), Hubei University of Chinese Medicine (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 25%
Seaweed-derived Bioactive Compounds
0.60
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