Diagnostic Accuracy of Tuberculosis Screening Tests in a Prospective Multinational Cohort: Chest Radiography With Computer-Aided Detection, Xpert Tuberculosis Host Response, and C-Reactive Protein
CAD4TB achieves target product profile targets and outperforms Xpert HR and CRP. Combining screening tests further increased accuracy. Clinical Trials Registration. NCT04923958.
Authors
- Charles Yu
- Payam Nahid (ORCID: https://orcid.org/0000-0003-2811-1311)
- Alfred Andama (ORCID: https://orcid.org/0000-0003-0526-0007)
- Patrick P. J. Phillips (ORCID: https://orcid.org/0000-0002-6336-7024)
- Claudia Maria Denkinger (ORCID: https://orcid.org/0000-0002-7216-7067)
- Devasahayam Jesudas Christopher (ORCID: https://orcid.org/0000-0002-9405-8494)
- Balamugesh Thangakunam
- Ankur Gupta‐Wright (ORCID: https://orcid.org/0000-0002-5150-2970)
- Welile V. Dube-Nwamba (ORCID: https://orcid.org/0000-0003-4231-1467)
- Victoria Dalay
- William O. Worodria (ORCID: https://orcid.org/0000-0002-8531-5567)
- Morten Rühwald (ORCID: https://orcid.org/0000-0002-1597-441X)
- Sandra V. Kik (ORCID: https://orcid.org/0000-0002-0662-4899)
- Rebecca Crowder (ORCID: https://orcid.org/0000-0001-6374-3088)
- Adithya Cattamanchi (ORCID: https://orcid.org/0000-0002-6553-2601)
- Grant Theron (ORCID: https://orcid.org/0000-0002-9216-2415)
- Nguyen Viet Nhung (ORCID: https://orcid.org/0000-0002-5447-133X)
- Dong Van Nguyen
Institutions
- South African Medical Research Council (ZA)
- FIND (CH)
- Christian Medical College, Vellore (IN)
- University of California, San Francisco (US)
- University of California, Irvine (US)
- Heidelberg University (DE)
- Stellenbosch University (ZA)
- Hatyai Hospital (TH)
- University Hospital Heidelberg (DE)
- German Center for Infection Research (DE)
- Hanoi Lung Hospital (VN)
- Imperial College London (GB)
- Makerere University (UG)
- De La Salle University – Dasmariñas (PH)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-11-05
- DOI
- https://doi.org/10.1093/cid/ciae549
- Citations
- 12
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 4.67