Variants in <scp><i>MICOS10</i></scp> Identified by Whole Genome Sequencing and <scp>RNA</scp> Sequencing in a New Type of Hepatocerebral Mitochondrial <scp>DNA</scp> Depletion Syndrome
Taken together, these findings indicate that MICOS10 is a causative gene for hepatopathy and neuropathy, a disease very similar to that associated with MICOS13.
Authors
- Yukiko Yatsuka (ORCID: https://orcid.org/0000-0003-3137-6919)
- Masaru Shimura (ORCID: https://orcid.org/0000-0002-1998-7349)
- Ayumu Sugiura (ORCID: https://orcid.org/0000-0002-4776-1478)
- Akira Ohtake (ORCID: https://orcid.org/0000-0003-1147-3113)
- Yoshihito Kishita (ORCID: https://orcid.org/0000-0003-4978-1680)
- Kohta Nakamura (ORCID: https://orcid.org/0009-0009-9109-7250)
- Toju Tanaka (ORCID: https://orcid.org/0000-0002-6065-8344)
- Yasushi Okazaki (ORCID: https://orcid.org/0000-0003-3241-5502)
- Kei Murayama (ORCID: https://orcid.org/0000-0002-3923-8636)
- Mitsuru Kubota (ORCID: https://orcid.org/0000-0002-5395-8226)
- Nanako Omichi
Institutions
- Juntendo University (JP)
- National Hospital Organization Hokkaido Medical Center (JP)
- Saitama Medical University Hospital (JP)
- National Center For Child Health and Development (JP)
- Chiba Hospital (JP)
- RIKEN Center for Integrative Medical Sciences (JP)
- Saitama Medical University (JP)
- Kindai University (JP)
Publication Details
- Journal
- Liver International
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1111/liv.16148
- Citations
- 1
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Japan Agency for Medical Research and Development
- Tokyo Biochemical Research Foundation
- Chugai Pharmaceutical
- Japan Society for the Promotion of Science