EZH1/2 plays critical roles in oocyte meiosis prophase I in mice
our study demonstrated that EZH1/2 plays a role in the DSBs repair in oocyte meiosis prophase I via multiple mechanisms and offers new insights into the physiological regulatory role of histone modification in fetal oocyte guardianship and female fertility.
Authors
- Shuangbo Kong (ORCID: https://orcid.org/0000-0002-7513-4041)
- Han Cai (ORCID: https://orcid.org/0000-0001-8509-6854)
- Ting Jiang (ORCID: https://orcid.org/0000-0002-6847-0020)
- Zhongxian Lu (ORCID: https://orcid.org/0000-0002-1682-7147)
- Xia-yin Cao
- Chengxiu Zhang
- Haibin Wang (ORCID: https://orcid.org/0000-0002-9865-324X)
- Yingpu Tian
- Jinhua Lu (ORCID: https://orcid.org/0000-0002-4164-4238)
Institutions
- Xiamen University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- Biological Research
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1186/s40659-024-00564-4
- Citations
- 3
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China