Mineralocorticoid receptor antagonism attenuates arteriovenous fistula stenosis by modulating the phenotype of vascular smooth muscle cells
Our study demonstrated that therapeutic targeting of MR may improve AVF outcome by modulating VSMC phenotypic switching. These findings offer promising avenues for further clinical investigations aimed at optimizing AVF outcomes in the hemodialysis population.
Authors
- Pei Wang (ORCID: https://orcid.org/0000-0002-1819-1365)
- Xianhui Liang
- Chunyu Zhou (ORCID: https://orcid.org/0000-0003-4608-7925)
- Yufei Wang (ORCID: https://orcid.org/0000-0002-5780-112X)
- Kai Chen (ORCID: https://orcid.org/0000-0002-8647-1182)
- Yamin Liu (ORCID: https://orcid.org/0000-0003-0031-7799)
- Bohan Chen (ORCID: https://orcid.org/0009-0009-5059-0145)
- Kai Wang (ORCID: https://orcid.org/0000-0002-6151-0034)
Institutions
- Nankai University (CN)
- Zhengzhou University (CN)
- Kaifeng University (CN)
- Kaifeng City Children's Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1093/ndt/gfae247
- Citations
- 2
- Primary Topic
- Vascular anomalies and interventions
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Natural Science Foundation of China
- Henan Provincial Science and Technology Research Project