Synthesis of benzosultams <i>via</i> Ag(<scp>i</scp>)-catalyzed alkylative cyclization of vinyl sulfonamides

A convenient method to access benzo-fused-γ-sultams <i>via</i> alkyl radical induced cyclization of vinyl sulfonamides is presented. A wide range of carboxylic acids including sterically hindered adamantanes participated as alkyl donors in this Ag(I)-catalyzed decarboxylative alkylation. The reaction utilizes readily available starting materials and demonstrates a broad substrate scope.

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Publication Details

Journal
Organic & Biomolecular Chemistry
Published
2024-11-08
DOI
https://doi.org/10.1039/d4ob01583e
Citations
2
Primary Topic
Organic and Inorganic Chemical Reactions
Type
article
Field-Weighted Citation Impact
0.48

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article

Synthesis of benzosultams via Ag(i)-catalyzed alkylative cyclization of vinyl sulfonamides

Remya Ramesh, Raju Dupud, Karthik Kumar Merugu, R Remyachand
2 citations
Organic & Biomolecular Chemistry
Organic and Inorganic Chemical Reactions
0.48
article

Synthesis of benzosultams via Ag(i)-catalyzed alkylative cyclization of vinyl sulfonamides

Remya Ramesh, Raju Dupud, Karthik Kumar Merugu, R Remyachand
article en
2 citations

Abstract

A convenient method to access benzo-fused-γ-sultams <i>via</i> alkyl radical induced cyclization of vinyl sulfonamides is presented. A wide range of carboxylic acids including sterically hindered adamantanes participated as alkyl donors in this Ag(I)-catalyzed decarboxylative alkylation. The reaction utilizes readily available starting materials and demonstrates a broad substrate scope.

Organic & Biomolecular ChemistryVol. 23(1)
Indian Institute of Chemical Technology (IN), Academy of Scientific and Innovative Research (IN)
Science and Engineering Research Board
Openalex Percentile: Top 39%
Organic and Inorganic Chemical Reactions
0.48
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