A single-cell transcriptomic map of the murine and human multiple myeloma immune microenvironment across disease stages
This resource provides a comprehensive and detailed immune atlas of the evolution in human and murine MM disease progression. Our findings can contribute to immune-based patient stratification and facilitate the development of novel and durable (immune) therapeutic strategies in MM.
Authors
- Ann De Becker (ORCID: https://orcid.org/0000-0003-0947-8708)
- Kevin Verstaen (ORCID: https://orcid.org/0000-0003-3582-0298)
- Emma Verheye (ORCID: https://orcid.org/0000-0002-0731-8762)
- Karin Vanderkerken (ORCID: https://orcid.org/0000-0002-2137-7179)
- Pauline M. R. Bardet (ORCID: https://orcid.org/0000-0003-4454-9823)
- Rong Fan (ORCID: https://orcid.org/0000-0003-1032-4546)
- Hatice Satilmis
- Kim De Veirman (ORCID: https://orcid.org/0000-0002-1313-6121)
- Daliya Kancheva (ORCID: https://orcid.org/0000-0001-6222-0461)
- Damya Laoui (ORCID: https://orcid.org/0000-0002-3373-1403)
- Niels Vandewalle (ORCID: https://orcid.org/0000-0003-4295-9394)
- Emile Clappaert (ORCID: https://orcid.org/0000-0003-1748-8666)
Institutions
- Vrije Universiteit Brussel (BE)
- Ghent University (BE)
- Universitair Ziekenhuis Brussel (BE)
- VIB-UGent Center for Inflammation Research (BE)
- VIB Single Cell Core
Publication Details
- Journal
- Journal of Hematology & Oncology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s13045-024-01629-3
- Citations
- 5
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Vrije Universiteit Brussel
- Koning Boudewijnstichting
- Kom op tegen Kanker
- Fondation contre le Cancer