Genetic Association of the Ins/Del Variant of ACE and Risk of Cardiomyopathy: A Case-Control Study and Updated Meta-Analysis
Our study found a significant association between the I/D polymorphism and cardiomyopathy risk in the Jammu population. Further, the meta-analysis strengthens the findings by consistently linking the ACE I/D polymorphism to both dilated and hypertrophic cardiomyopathy. These results underscore the importance of genetic factors in cardiomyopathy risk assessment and further research is needed to understand the underlying mechanisms and potential therapeutic implications.
Authors
- Parvinder Kumar (ORCID: https://orcid.org/0000-0003-1039-6638)
- Mohd Younis (ORCID: https://orcid.org/0000-0002-4328-1776)
- Ashiq Hussain Mir (ORCID: https://orcid.org/0000-0002-3240-6852)
- A. Najitha Banu (ORCID: https://orcid.org/0000-0002-3847-0441)
- Meenakshi Bhagat (ORCID: https://orcid.org/0009-0005-3538-9671)
- Shikha Bharti
- Amrit Sudershan (ORCID: https://orcid.org/0000-0001-9439-6736)
- Rakesh K. Panjalyia
- Sheetal Bhagat
- Surbhi Pathania
- Dharminder Kumar
- Mayushi Gupta
- Ishan Behlam
Institutions
- Lovely Professional University (IN)
- University of Jammu (IN)
- Maharishi Markandeshwar University, Mullana (IN)
- Government of India (IN)
- Sri Sai University (IN)
- Government Medical College (IN)
Publication Details
- Journal
- Cardiology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1159/000542278
- Citations
- 1
- Primary Topic
- Cardiovascular Effects of Exercise
- Type
- article
- Field-Weighted Citation Impact
- 0.40