Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
This study introduces the possibility that the clinical effects of targeting IL-5/IL-5Rα in severe asthma may also involve reduction of MC populations.
Authors
- Urška Bidovec‐Stojkovič (ORCID: https://orcid.org/0000-0001-8978-6887)
- Sabina Škrgat (ORCID: https://orcid.org/0000-0002-0136-4733)
- Oscar E. Simonson (ORCID: https://orcid.org/0000-0002-3552-5558)
- Ana Koren (ORCID: https://orcid.org/0000-0002-9671-1645)
- Jenny Hallgren (ORCID: https://orcid.org/0000-0002-3685-5364)
- Andreï Malinovschi (ORCID: https://orcid.org/0000-0002-4098-7765)
- Erika Méndez-Enríquez (ORCID: https://orcid.org/0000-0002-2114-2812)
- Barbro Dahlén (ORCID: https://orcid.org/0000-0003-3803-9034)
- Peter Korošec (ORCID: https://orcid.org/0000-0002-0835-1599)
- Christer Janson (ORCID: https://orcid.org/0000-0001-5093-6980)
- Perla Abigail Alvarado-Vazquez (ORCID: https://orcid.org/0000-0003-4623-3478)
- Valentyna Yasinska (ORCID: https://orcid.org/0000-0002-1379-1265)
- Gunnar Pejler (ORCID: https://orcid.org/0000-0002-6779-391X)
- Peter Kopač (ORCID: https://orcid.org/0000-0001-7261-6689)
- Maya Salomonsson
Institutions
- Uppsala University (SE)
- Karolinska University Hospital (SE)
- Uppsala University Hospital (SE)
- Ljubljana University Medical Centre (SI)
- Karolinska Institutet (SE)
- University Clinic of Pulmonary and Allergic Diseases Golnik (SI)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1016/j.jaci.2024.10.025
- Citations
- 13
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.25