Associations of physiologic subtypes based on HOMA2 indices of β-cell function and insulin sensitivity with the risk of kidney function decline, cardiovascular disease, and all-cause mortality from the 4C study
The classical subtype had the strongest correlation with the risk of kidney function decline, and the hyperinsulinemic subtype had the highest risk of CVD and all-cause mortality, which should be considered for interventions with precision medicine.
Authors
- Danpei Li (ORCID: https://orcid.org/0000-0003-4972-976X)
- Xiaoyu Meng (ORCID: https://orcid.org/0000-0002-5239-6866)
- Yaming Guo
- Xuefeng Yu (ORCID: https://orcid.org/0000-0003-3961-9321)
- Zhelong Liu (ORCID: https://orcid.org/0000-0003-2567-2287)
- Peiqiong Luo (ORCID: https://orcid.org/0009-0000-2712-5856)
- Limeng Pan
- Yuxi Xiang
- Benping Zhang (ORCID: https://orcid.org/0000-0001-9107-6833)
- Ranran Kan (ORCID: https://orcid.org/0009-0001-2829-945X)
- Junhui Xie
- Wentao He (ORCID: https://orcid.org/0000-0002-6319-1639)
- Yan Yang (ORCID: https://orcid.org/0000-0001-8146-8040)
- Beibei Mao (ORCID: https://orcid.org/0009-0008-7257-144X)
- Shuhong Hu (ORCID: https://orcid.org/0000-0002-3878-1469)
- Yi He (ORCID: https://orcid.org/0000-0003-4511-5461)
- Xinrong Zhou
- Siyi Wang (ORCID: https://orcid.org/0009-0006-4909-2569)
Institutions
- National Clinical Research Center for Digestive Diseases (CN)
- National Clinical Research (US)
- Tongji Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s12933-024-02496-5
- Citations
- 1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- National Natural Science Foundation of China