Decreased Expression of the EAAT5 Glutamate Transporter at Photoreceptor Synapses in Early, Pre-Clinical Experimental Autoimmune Encephalomyelitis, a Mouse Model of Multiple Sclerosis
Our data illustrate early alterations of the EAAT5 glutamate transporter in the early pre-clinical phase of EAE/MS and suggest an involvement of EAAT5 in the previously observed early synaptic changes at photoreceptor synapses. The precise mechanisms need to be elucidated by future investigations.
Authors
- Dalia R. Ibrahim (ORCID: https://orcid.org/0000-0003-0819-2193)
- Abdul Samad (ORCID: https://orcid.org/0000-0001-9647-2165)
- Karin Schwarz (ORCID: https://orcid.org/0000-0002-7328-1427)
- Frank Schmitz (ORCID: https://orcid.org/0000-0003-1457-6222)
- Julia Jaffal
Institutions
- Saarland University (DE)
Publication Details
- Journal
- Biomedicines
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3390/biomedicines12112545
- Citations
- 4
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- Dr. Rolf M. Schwiete Stiftung