A Sensitive and Quick Fluorescent Sensor for the “Turn‐On” Detection and Imaging of Glutathione Based on Sulfur Quantum Dots and MnO<sub>2</sub> Nanosheets
Glutathione (GSH) is one of the most abundant bioethanol antioxidants in living cells. Here, a fluorescent probe based on MnO<sub>2</sub> nanosheets and sulfur quantum dots (SQDs) was fabricated. Because of the synergistic effect of IFE and FRET, the fluorescence from SQDs was quenched by MnO<sub>2</sub> nanosheets. In the presence of GSH, the fluorescence of SQDs could be recovered because of the reduction of MnO<sub>2</sub> nanosheets by GSH. The method can detect GSH in the concentration range of 5 ~ 1000 μM with the detection limit as low as 1.26 μM. This quick, easy, and cost-effective sensor could be used for the quantification of GSH in serum samples and the imaging of GSH in Escherichia coli O157:H7.
Authors
- Huifeng Xu (ORCID: https://orcid.org/0000-0002-0592-884X)
- Zhenlin Hu (ORCID: https://orcid.org/0000-0001-5529-397X)
- Leyao Zhang
- Min Cheng (ORCID: https://orcid.org/0000-0003-1086-4008)
- Xi Zhu (ORCID: https://orcid.org/0000-0002-2496-4053)
- Y.-H. Percival Zhang
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Agriculture and Forestry University (CN)
Publication Details
- Journal
- Luminescence
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1002/bio.4929
- Citations
- 3
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.88
Funders
- National Natural Science Foundation of China