Heterogeneity in Reported Side Effects Following Initiation of Elexacaftor‐Tezacaftor‐Ivacaftor: Experiences at a Quaternary CF Care Center
Responses demonstrated marked heterogeneity, with most respondents reporting at least one side effect following initiation. Dose modification was commonly utilized to mitigate adverse effects, however few respondents had to discontinue treatment. These findings demonstrate the importance of monitoring for potential drug-related side effects of ETI in clinical settings.
Authors
- Lena Papadakis (ORCID: https://orcid.org/0009-0002-8709-4937)
- Lael M. Yonker (ORCID: https://orcid.org/0000-0003-1711-8227)
- Lindsay Bringhurst
- Margot Hardcastle
- Isabel P. Neuringer
- Leonard Sicilian
- C. Richards (ORCID: https://orcid.org/0000-0003-1182-0613)
- Jacqueline Mombourquette
- Julia Zweifach
- Tayler Stander
- Brenden Lawton
Institutions
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Pediatric Pulmonology
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1002/ppul.27382
- Citations
- 7
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 2.93