Combined inhibition of histone methyltransferases <scp>EZH2</scp> and <scp>DOT1L</scp> is an effective therapy for neuroblastoma
Our results support further investigation of HMT inhibitor combinations as a therapeutic approach in NB.
Authors
- Michael W. Parker (ORCID: https://orcid.org/0000-0002-3101-1138)
- Anushree Balachandran
- Vicki Zhai
- Murray D. Norris (ORCID: https://orcid.org/0000-0002-0632-4589)
- Belamy B. Cheung (ORCID: https://orcid.org/0000-0001-8784-860X)
- Ernest Hung Yu Ng (ORCID: https://orcid.org/0000-0002-7688-4557)
- Matthew Wai Kin Wong (ORCID: https://orcid.org/0000-0001-6913-4558)
- Tracy L. Nero (ORCID: https://orcid.org/0000-0002-3393-1843)
- Sukriti Krishan (ORCID: https://orcid.org/0000-0002-8864-1480)
- Janith A. Seneviratne (ORCID: https://orcid.org/0000-0003-0413-5829)
- Michelle Haber (ORCID: https://orcid.org/0000-0003-2036-8817)
- Amit Lalwani (ORCID: https://orcid.org/0000-0003-3458-3489)
- Daniel R. Carter
- Daenikka Ravindrarajah
- Tao Liu (ORCID: https://orcid.org/0000-0001-6244-7316)
- G M Marshall
- Ruby Pandher
- Shudong Wang
Institutions
- University of Technology Sydney (AU)
- The University of Melbourne (AU)
- University of South Australia (AU)
- UNSW Sydney (AU)
- Children's Cancer Institute Australia (AU)
- Sydney Children's Hospital (AU)
- St Vincents Institute of Medical Research (AU)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1002/cam4.70082
- Citations
- 5
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- Cancer Australia
- Cancer Institute NSW
- Kids' Cancer Project
- National Health and Medical Research Council
- Cancer Council NSW