A prospective multi-cohort study identifies and validates a 5-gene peripheral blood signature predictive of immunotherapy response in non-small cell lung cancer
Our study confirms a 5-gene signature as a key biomarker for ICI response in NSCLC, enhancing treatment precision.
Authors
- Junlong Wang (ORCID: https://orcid.org/0000-0002-3969-3321)
- Jeffrey A. Borgia (ORCID: https://orcid.org/0000-0002-1520-7966)
- Shaoqiu Chen (ORCID: https://orcid.org/0000-0001-6532-1575)
- Mayumi Jijiwa (ORCID: https://orcid.org/0000-0003-1596-856X)
- Xiaoyan Wang (ORCID: https://orcid.org/0000-0002-8763-289X)
- Fangfang Liu (ORCID: https://orcid.org/0000-0003-1059-8598)
- Yuanyuan Fu (ORCID: https://orcid.org/0000-0001-7715-0558)
- Ting Gong (ORCID: https://orcid.org/0000-0003-4844-0227)
- Hongwei Wang (ORCID: https://orcid.org/0000-0003-0697-5100)
- Youping Deng
- Zhougui Ling (ORCID: https://orcid.org/0000-0003-1611-8946)
- Chun Deng
- Qian Chu (ORCID: https://orcid.org/0000-0001-8192-7630)
- A Ayman
- Masaki Nasu
- Hua Yang
Institutions
- University of Hawaiʻi at Mānoa (US)
- Rush University Medical Center (US)
- Shanghai Jiao Tong University (CN)
- Queen's Medical Center (US)
- Fourth Affiliated Hospital of Guangxi Medical University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Molecular Cancer
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1186/s12943-024-02160-2
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- National Institutes of Health