Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors
TUNIMO-NCT04695327. Registered 4 January 2021, https://clinicaltrials.gov/study/NCT04695327 . TUNINTIL-NCT04217473. Registered 19 December 2019, https://clinicaltrials.gov/study/NCT04217473 . PROTA-NCT05271318. Registered 4 February 2022, https://clinicaltrials.gov/study/NCT05271318 .
Authors
- Matthew Stephen Block (ORCID: https://orcid.org/0000-0001-5692-4219)
- Amir Khammari (ORCID: https://orcid.org/0000-0001-9328-8004)
- Brigitte Dréno (ORCID: https://orcid.org/0000-0001-5574-5825)
- Santeri A. Pakola (ORCID: https://orcid.org/0000-0001-6235-8612)
- K. Jalkanen (ORCID: https://orcid.org/0000-0003-4497-5371)
- Anna Kanerva (ORCID: https://orcid.org/0000-0003-3355-7393)
- Elise Jirovec (ORCID: https://orcid.org/0009-0004-0606-6577)
- Tatiana V. Kudling (ORCID: https://orcid.org/0000-0003-4481-1617)
- Victor Arias (ORCID: https://orcid.org/0000-0002-3631-2896)
- James H.A. Clubb (ORCID: https://orcid.org/0000-0002-9146-4817)
- Tine Monberg (ORCID: https://orcid.org/0000-0002-7217-2974)
- Inge Marie Svane (ORCID: https://orcid.org/0000-0002-9451-6037)
- Lyna Haybout (ORCID: https://orcid.org/0009-0005-5170-5611)
- Dafne C.A. Quixabeira (ORCID: https://orcid.org/0000-0003-2614-3942)
- Akseli Hemminki (ORCID: https://orcid.org/0000-0001-7103-8530)
- Suvi Sorsa (ORCID: https://orcid.org/0009-0002-1709-611X)
- Tuomo Alanko (ORCID: https://orcid.org/0000-0002-1649-9040)
- João M. Santos (ORCID: https://orcid.org/0000-0003-4639-1644)
- Daniel A. Adamo (ORCID: https://orcid.org/0000-0003-1420-7785)
- Víctor Cervera-Carrascón (ORCID: https://orcid.org/0000-0001-6684-3666)
- Otto Hemminki (ORCID: https://orcid.org/0000-0002-3396-2391)
- Johanna Mäenpää (ORCID: https://orcid.org/0000-0003-0486-6912)
- Claudia Kistler
Institutions
- Centre National de la Recherche Scientifique (FR)
- Mayo Clinic (US)
- University of Helsinki (FI)
- Inserm (FR)
- Helsinki University Hospital (FI)
- Copenhagen University Hospital (DK)
- Biocenter Finland (FI)
- Ministry of Finance (FI)
- Tampere University Hospital (FI)
- Docrates Cancer Center (FI)
- Hospital District of Helsinki and Uusimaa (FI)
- Immunologie et Nouveaux Concepts en Immunothérapie
- Nantes Université (FR)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1186/s13046-024-03219-0
- Citations
- 15
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 8.25
Funders
- Helsingin Yliopisto
- Biocenter Finland
- Helsinki Institute of Life Science, Helsingin Yliopisto