Association of artificial intelligence-based immunoscore with the efficacy of chemoimmunotherapy in patients with advanced non-squamous non-small cell lung cancer: a multicentre retrospective study
Our study indicates that AI-powered immunoscore applied on LUAD digital slides can serve as a biomarker for survival outcomes in patients with advanced non-squamous NSCLC who received chemoimmunotherapy. This methodology could be applied to other cancers and facilitate cancer immunotherapy.
Authors
- Yuanyuan Zhao (ORCID: https://orcid.org/0000-0002-7148-7608)
- Yunpeng Yang (ORCID: https://orcid.org/0000-0001-5163-0940)
- Wen‐Feng Fang (ORCID: https://orcid.org/0000-0003-0350-9059)
- Jiayi Shen (ORCID: https://orcid.org/0000-0002-7022-6940)
- Huaqiang Zhou (ORCID: https://orcid.org/0000-0003-3538-4481)
- Yaxiong Zhang (ORCID: https://orcid.org/0009-0001-9880-3834)
- Shaodong Hong (ORCID: https://orcid.org/0000-0002-5632-6857)
- Li Zhang (ORCID: https://orcid.org/0000-0002-6672-4808)
- Xue Hou (ORCID: https://orcid.org/0000-0002-5552-7569)
- Yuxiang Ma (ORCID: https://orcid.org/0000-0003-1173-8441)
- Dongchen Sun (ORCID: https://orcid.org/0000-0002-7598-3326)
- Yan Huang (ORCID: https://orcid.org/0000-0002-4331-0581)
- Jianhua Zhan
- Bingfang He
- Shuoyu Xu
- Hongyun Zhao
- Wenjuan Ma
- Jiaqing Liu (ORCID: https://orcid.org/0009-0003-8777-8375)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
- State Key Laboratory of Oncology in South China
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-06
- DOI
- https://doi.org/10.3389/fimmu.2024.1485703
- Citations
- 3
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.85