Rbbp6-Mediated Bmal1 Ubiquitination Inhibits YAP1 Signaling Pathway to Promote Ferroptosis in Diabetes-Induced Testicular Damage
Rbbp6-mediated Bmal1 ubiquitination suppressed YAP1 pathway, promoting ferroptosis in DITD. This study highlighted Rbbp6/Bmal1/YAP1 axis as a potential therapeutic target for mitigating DITD.
Authors
- Zhiqiang Zhu (ORCID: https://orcid.org/0000-0002-1277-5917)
- Jun Qiao (ORCID: https://orcid.org/0000-0001-7038-4538)
- Bei Liu (ORCID: https://orcid.org/0000-0003-2155-2974)
- Yuan Tian (ORCID: https://orcid.org/0009-0008-3642-2236)
- Yue‐Hai Xiao
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Diabetes & Metabolism Journal
- Published
- 2024-11-06
- DOI
- https://doi.org/10.4093/dmj.2024.0099
- Citations
- 6
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China
- Guizhou Medical University