Palladium‐Catalyzed Domino Synthesis of Sulfone‐Containing 1,3‐Enynes from Simple Alkynes and Sulfonyl Iodides

Abstract A palladium‐catalyzed domino radical sulfonylation and alkynylation of simple alkynes has been developed for the rapid construction of privileged scaffolds containing sulfone and 1,3‐enyne motifs. The reaction of sulfonyl iodide with simple alkynes proceeded smoothly under mild conditions to afford a variety of sulfone‐containing 1,3‐enynes in good yields and with excellent selectivities.