Metabolomics and proteomics insights into hepatic responses of weaned piglets to dietary Spirulina inclusion and lysozyme supplementation
While Spirulina inclusion had some adverse effects on growth performance, it also enhanced hepatic metabolic efficiency by improving fatty acid oxidation, carbohydrate catabolism and cellular defence mechanisms. The addition of lysozyme further improved these benefits by reducing some of the negative impacts on growth and enhancing nutrient digestibility, tissue regeneration, and overall metabolic balance. Together, Spirulina and lysozyme demonstrate potential as functional dietary components, but further optimization is needed to fully realize their benefits without compromising growth performance.
Authors
- José A. M. Prates (ORCID: https://orcid.org/0000-0003-1032-5987)
- P.D. Eckersall (ORCID: https://orcid.org/0000-0001-5254-5502)
- J.P.B. Freire (ORCID: https://orcid.org/0000-0002-1811-4378)
- Manólis Matzapetákis (ORCID: https://orcid.org/0000-0001-9730-0621)
- André M. Almeida (ORCID: https://orcid.org/0000-0002-7810-3988)
- Nicolas Guillemin (ORCID: https://orcid.org/0000-0003-2220-3901)
- Anita Horvatić (ORCID: https://orcid.org/0000-0001-9625-1450)
- Josipa Kuleš (ORCID: https://orcid.org/0000-0002-4945-4690)
- David M. Ribeiro (ORCID: https://orcid.org/0000-0002-0990-7739)
- Cátia F. Martins (ORCID: https://orcid.org/0000-0002-1017-3269)
Institutions
- University of Lisbon (PT)
- University of Zagreb (HR)
- University of Glasgow (GB)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1186/s12917-024-04339-7
- Citations
- 5
- Primary Topic
- Animal Nutrition and Physiology
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- European Commission
- Fundação para a Ciência e a Tecnologia
- Division of Materials Research