Effects of multiple‐dose administration of zavegepant nasal spray on the single‐dose pharmacokinetics of ethinyl estradiol‐levonorgestrel

Co-administration of zavegepant nasal spray with a single dose of an oral contraceptive resulted in no clinically meaningful changes (<12% increase) in EE-LNG exposure.

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Publication Details

Journal
Headache The Journal of Head and Face Pain
Published
2024-11-05
DOI
https://doi.org/10.1111/head.14863
Citations
3
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
1.16

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article

Effects of multiple‐dose administration of zavegepant nasal spray on the single‐dose pharmacokinetics of ethinyl estradiol‐levonorgestrel

Richard Bertz, Julie L. Collins, Kyle Matschke, Jennifer Madonia et al.
3 citations
Headache The Journal of Head and Face Pain
Migraine and Headache Studies
1.16
article

Effects of multiple‐dose administration of zavegepant nasal spray on the single‐dose pharmacokinetics of ethinyl estradiol‐levonorgestrel

Richard Bertz, Julie L. Collins, Kyle Matschke, Jennifer Madonia, Jing Liu, Rajinder Bhardwaj
article en
3 citations

Abstract

Co-administration of zavegepant nasal spray with a single dose of an oral contraceptive resulted in no clinically meaningful changes (<12% increase) in EE-LNG exposure.

Headache The Journal of Head and Face PainVol. 65(1)
Pfizer (United States) (US), Biohaven Pharmaceuticals (United States) (US), Certara (United States) (US), Integra LifeSciences (United States) (US)
Pfizer
Good health and well-being
Openalex Percentile: Top 20%
Migraine and Headache Studies
1.16
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