CKD in Bardet-Biedl Syndrome: Evidence Supporting Multifactorial Etiology
The present study suggests that BBS is a condition of vulnerability to develop kidney disease, and that age, hypertension and obesity are associated with eGFR decline in adult patients with BBS. Whether effective interventions to treat modifiable factors will reduce CKD risk requires further studies.
Authors
- Andrea Melluso (ORCID: https://orcid.org/0000-0002-6155-2138)
- Giovanna Capolongo (ORCID: https://orcid.org/0000-0002-5134-3826)
- Miriam Zacchia (ORCID: https://orcid.org/0000-0003-0376-2783)
- Francesca Simonelli (ORCID: https://orcid.org/0000-0001-8520-6769)
- Francesca Del Vecchio Blanco (ORCID: https://orcid.org/0000-0002-9454-2964)
- Giovambattista Capasso (ORCID: https://orcid.org/0000-0003-3469-8614)
- Vincenzo Nigro (ORCID: https://orcid.org/0000-0002-3378-5006)
- Giulio Piluso (ORCID: https://orcid.org/0000-0001-9418-125X)
- Valentina Di Iorio (ORCID: https://orcid.org/0000-0002-8179-5970)
- Floriana Secondulfo (ORCID: https://orcid.org/0000-0002-5638-0837)
- Alessandra Perna (ORCID: https://orcid.org/0000-0003-4048-9392)
- Annalaura Torella (ORCID: https://orcid.org/0000-0003-2479-6018)
- Francesco Trepiccione
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- Biogem (IT)
- Telethon Institute Of Genetics And Medicine (IT)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1016/j.ekir.2024.10.030
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Rare Kidney Disease Reference Network