Evaluation of the clinical performance of anti-mutated citrullinated vimentin antibody and 14-3-3 eta testing in rheumatoid arthritis
Individually, 14-3-3 eta, anti-MCV and CCP3.1 assays had ≥90 % specificity in diagnosed RA patients, with better sensitivities for anti-MCV and CCP3.1 than 14-3-3 eta. Overall diagnostic performance of anti-MCV was similar to CCP3.1 and RF, all of which outperformed 14-3-3 eta in our cohort.
Authors
- Heather A. Nelson (ORCID: https://orcid.org/0000-0002-4622-2923)
- Thomas B. Martins (ORCID: https://orcid.org/0000-0003-3116-0800)
- Vijayalakshmi Nandakumar
- Abdulrahman Saadalla (ORCID: https://orcid.org/0000-0002-3175-3967)
Institutions
- University of Utah (US)
- ARUP Institute for Clinical and Experimental Pathology
- ARUP Laboratories (United States) (US)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1515/cclm-2024-1112
- Citations
- 2
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- ARUP Institute for Clinical and Experimental Pathology