Evolutionary Characteristics in Primary Aldosteronism Patients
This study demonstrated a genetic and transcriptome landscape of aldosterone-producing structures and adjacent hyperplasia glands in primary aldosteronism. The results indicated independent clonal origins on functional nodules and hyperplasia tissues, and little mutual evolutionary relationship was found on their phylogenetic trees.
Authors
- Anli Tong (ORCID: https://orcid.org/0000-0002-1418-1012)
- Min Nie (ORCID: https://orcid.org/0000-0001-7179-0044)
- Yue Zhou (ORCID: https://orcid.org/0000-0002-2639-6934)
- Yu Wang (ORCID: https://orcid.org/0009-0005-9856-9979)
- Yinjie Gao (ORCID: https://orcid.org/0000-0001-6034-1999)
- Xiaoyan Chang (ORCID: https://orcid.org/0000-0002-0732-6551)
- Y. Zhang (ORCID: https://orcid.org/0009-0007-3331-1082)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
Publication Details
- Journal
- Hypertension
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1161/hypertensionaha.124.23398
- Citations
- 3
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 1.07