Yigu decoction regulates plasma miRNA in postmenopausal osteoporosis patients: a randomized controlled trial
This study demonstrated that YGD is beneficial in the treatment of PMOP, ameliorating clinical symptoms and bone turnover indices. Moreover, the inhibition of miR-133a-3p expression may be the key mechanisms by which YGD regulates bone metabolism in the treatment of PMOP, although YGD regulates bone metabolism in a multitarget and multipathway manner.
Authors
- Ruikun Zhang (ORCID: https://orcid.org/0000-0003-3993-7864)
- Guijin Li (ORCID: https://orcid.org/0000-0002-0856-0585)
- Kun Yan (ORCID: https://orcid.org/0000-0002-1738-9708)
- Xinmiao Yao (ORCID: https://orcid.org/0000-0002-4232-7509)
- Zhineng Chen
- Haifeng Chen (ORCID: https://orcid.org/0000-0002-7496-4182)
- Ziqi Wu (ORCID: https://orcid.org/0000-0001-7654-2496)
- Yang Zhang (ORCID: https://orcid.org/0009-0008-3577-6286)
Institutions
- Zhejiang Chinese Medical University (CN)
- The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-06
- DOI
- https://doi.org/10.3389/fphar.2024.1460906
- Citations
- 1
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.23