Transcriptome Profiles Characteristics of the Peripheral Immune in Patients with Severe Fever with Thrombocytopenia Syndrome
Overall, our research findings systematically observed potential immune mechanisms underlying clinical symptom heterogeneity and noteworthily revealed multiple signaling pathways leading to coagulation dysfunction in fatal outcomes, not just related to decreased platelet count, which can further elucidate the interaction between viruses and hosts and contribute to clinical treatment.
Authors
- Caiyun Chang
- Qing Duan (ORCID: https://orcid.org/0000-0003-4467-7024)
- Zhi‐Hong Wen (ORCID: https://orcid.org/0000-0003-4411-044X)
- Xiangjuan Chen
- Qingshuai Sun (ORCID: https://orcid.org/0000-0001-6145-0599)
- Yuwei Zhang (ORCID: https://orcid.org/0000-0003-1289-4171)
- Tao Liu (ORCID: https://orcid.org/0000-0002-0506-3356)
- Xiaomei Zhang (ORCID: https://orcid.org/0009-0000-5875-4284)
- Bo Pang (ORCID: https://orcid.org/0000-0001-6672-2346)
- Xiaolin Jiang (ORCID: https://orcid.org/0000-0002-8162-0468)
Institutions
- Weifang Medical University (CN)
- Shandong First Medical University (CN)
- Shandong Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/jir.s485118
- Citations
- 1
- Primary Topic
- Viral Infections and Vectors
- Type
- article
- Field-Weighted Citation Impact
- 0.39