Oral cyclophosphamide monotherapy in advanced resistant ocular cicatricial pemphigoid

The prognosis of advanced OCP in patients is unlikely to be altered by the stepladder approach and step-up strategy. While oral cyclophosphamide can be efficacious for remission induction in resistant and aggressive OCP cases, a step-down strategy employing less potent agents with safer side effect profiles should be contemplated for subsequent treatment.

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Publication Details

Journal
Taiwan Journal of Ophthalmology
Published
2024-11-06
DOI
https://doi.org/10.4103/tjo.tjo-d-24-00057
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Oral cyclophosphamide monotherapy in advanced resistant ocular cicatricial pemphigoid

Andrew Dolinko, Peter Y. Chang, Arash Maleki, Tate Valerio et al.
Taiwan Journal of Ophthalmology
Autoimmune Bullous Skin Diseases
article

Oral cyclophosphamide monotherapy in advanced resistant ocular cicatricial pemphigoid

Andrew Dolinko, Peter Y. Chang, Arash Maleki, Tate Valerio, C. Stephen Foster, Hasan Bashir, Yasmin Massoudi, Soheila Asgari, Stephen D. Anesi, Allison Richey
article en

Abstract

The prognosis of advanced OCP in patients is unlikely to be altered by the stepladder approach and step-up strategy. While oral cyclophosphamide can be efficacious for remission induction in resistant and aggressive OCP cases, a step-down strategy employing less potent agents with safer side effect profiles should be contemplated for subsequent treatment.

Taiwan Journal of OphthalmologyVol. 15(2)
Harvard University (US), Noor Eye Hospital (IR), University of Florida (US), Ocular Immunology and Uveitis Foundation (US), Massachusetts Eye Research and Surgery Institute (US)
Good health and well-being
Openalex Percentile: Top 68%
Autoimmune Bullous Skin Diseases
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