Higher detectability of amyloid with phenol Congo red compared with alkaline Congo red
The use of PHCR staining as a screening method in suspected amyloidosis improves amyloid (light chain, transthyretin, and amyloid A protein) detectability in various tissues. The PHCR staining specificity should be verified via electron microscopy and/or mass spectrometry.
Authors
- Ewa Walczak
- Marta Legatowicz-Koprowska
- Małgorzata Mańczak (ORCID: https://orcid.org/0000-0002-0736-0389)
- Justyna Szczygieł (ORCID: https://orcid.org/0009-0008-8712-6453)
Institutions
- National Institute of Geriatrics, Rheumatology and Rehabilitation (PL)
- Institute of Cardiology (PL)
- Cardinal Stefan Wyszynski University in Warsaw (PL)
Publication Details
- Journal
- Reumatologia/Rheumatology
- Published
- 2024-11-06
- DOI
- https://doi.org/10.5114/reum/192390
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji im. Prof. dr hab. med. Eleonory Reicher