Molecular cloning of PRD-like homeobox genes expressed in bovine oocytes and early IVF embryos

Providing full-length cDNA evidence for previously predicted homeobox genes that belong to PRDL class improves the annotation of the bovine genome. Updating the annotation with seven developmentally-important genes will enhance the accuracy of RNAseq analysis with datasets derived from bovine preimplantation embryos. In addition, the absence of TPRX3 in humans highlights the species-specific and TF-specific regulation of biological processes during early embryo development.

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Publication Details

Journal
BMC Genomics
Published
2024-11-06
DOI
https://doi.org/10.1186/s12864-024-10969-w
Citations
4
Primary Topic
Animal Genetics and Reproduction
Type
article
Field-Weighted Citation Impact
2.20

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Molecular cloning of PRD-like homeobox genes expressed in bovine oocytes and early IVF embryos

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4 citations
BMC Genomics
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article

Molecular cloning of PRD-like homeobox genes expressed in bovine oocytes and early IVF embryos

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article en
4 citations

Abstract

Providing full-length cDNA evidence for previously predicted homeobox genes that belong to PRDL class improves the annotation of the bovine genome. Updating the annotation with seven developmentally-important genes will enhance the accuracy of RNAseq analysis with datasets derived from bovine preimplantation embryos. In addition, the absence of TPRX3 in humans highlights the species-specific and TF-specific regulation of biological processes during early embryo development.

BMC GenomicsVol. 25(1)
University of Helsinki (FI), University of Basel (CH), Estonian University of Life Sciences (EE), Helsinki University Hospital (FI), Karolinska Institutet (SE), Folkhälsans Forskningscentrum (FI), University of Tartu (EE)
European Commission, Jane ja Aatos Erkon Säätiö, Karolinska Institutet, Vetenskapsrådet, Sigrid Juséliuksen Säätiö, Tartu Ülikool, Institute of Molecular and Cell Biology
Life in Land
Openalex Percentile: Top 11%
Animal Genetics and Reproduction
2.20
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