Diastereoselective Double Annulation of Allenoates with Povarov Adducts: Modular Synthesis of Multisubstituted Pyrroloquinolines

Herein, we report an atom-economical, one-pot, four-component, diastereoselective double-annulation reaction to construct polyfused pyrroloquinolines. This reaction highlights the cyclization of in situ<i>-</i>formed Povarov adducts with allenoates for the first time.

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Publication Details

Journal
The Journal of Organic Chemistry
Published
2024-11-06
DOI
https://doi.org/10.1021/acs.joc.4c02161
Citations
4
Primary Topic
Asymmetric Synthesis and Catalysis
Type
article
Field-Weighted Citation Impact
1.00

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article

Diastereoselective Double Annulation of Allenoates with Povarov Adducts: Modular Synthesis of Multisubstituted Pyrroloquinolines

Srinivasarao Yaragorla, Doma Arun
4 citations
The Journal of Organic Chemistry
Asymmetric Synthesis and Catalysis
1.00
article

Diastereoselective Double Annulation of Allenoates with Povarov Adducts: Modular Synthesis of Multisubstituted Pyrroloquinolines

Srinivasarao Yaragorla, Doma Arun
article en
4 citations

Abstract

Herein, we report an atom-economical, one-pot, four-component, diastereoselective double-annulation reaction to construct polyfused pyrroloquinolines. This reaction highlights the cyclization of in situ<i>-</i>formed Povarov adducts with allenoates for the first time.

The Journal of Organic ChemistryVol. 89(22)
University of Hyderabad (IN)
Ministry of Education, India, University of Hyderabad, Science and Engineering Research Board
Zero hunger
Openalex Percentile: Top 26%
Asymmetric Synthesis and Catalysis
1.00
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