Determining the Relationship Between Corneal Stiffening and Tissue Dehydration After Corneal Cross-Linking
Corneal tissue hydration changes significantly impact measured corneal stiffness after CXL using mechanical testing. Not considering H leads to major overestimation of the stiffening effect of the CXL procedure. Depth-dependence of corneal thickness because of changing hydration is strongly dependent on the integrity of the tissue.
Authors
- Joshua N. Webb (ORCID: https://orcid.org/0000-0002-7464-6678)
- J. Bradley Randleman
- Giuliano Scarcelli (ORCID: https://orcid.org/0000-0002-1736-077X)
- Raymundo Rodríguez-López (ORCID: https://orcid.org/0000-0002-9034-352X)
- Peter Kofinas (ORCID: https://orcid.org/0000-0001-6657-3037)
- Metecan Erdi (ORCID: https://orcid.org/0000-0001-9267-654X)
- Walfre Franco (ORCID: https://orcid.org/0000-0003-0905-4083)
- Hongyuan Zhang (ORCID: https://orcid.org/0000-0002-4949-6882)
Institutions
- Cleveland Clinic (US)
- University of Massachusetts Lowell (US)
- University of Massachusetts Chan Medical School (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Cleveland Eye Clinic (US)
- Case Western Reserve University (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1167/iovs.65.13.14
- Citations
- 4
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- Research to Prevent Blindness
- Cleveland Clinic
- National Institutes of Health