Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

This study significantly advances our understanding of the intricate cellular and molecular mechanisms underlying retinal neovascularization, emphasizing the pivotal role of Müller cells. The identified pathways provide valuable insights into potential therapeutic targets for PDR, offering promising directions for further research and clinical interventions.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2024-11-06
DOI
https://doi.org/10.1167/iovs.65.13.8
Citations
5
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
1.17

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article

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

Xueming Yao, Siyue Chen, Xue Dong, Kai He et al.
5 citations
Investigative Ophthalmology & Visual Science
Retinal Development and Disorders
1.17
article

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

Xueming Yao, Siyue Chen, Xue Dong, Kai He, Qing Liu, Xiaohong Wang, Ziqi Li, Ju Guo, Hua Yan, Haokun Zhang, Yi Lei, Mulin Jun Li
article en
5 citations

Abstract

This study significantly advances our understanding of the intricate cellular and molecular mechanisms underlying retinal neovascularization, emphasizing the pivotal role of Müller cells. The identified pathways provide valuable insights into potential therapeutic targets for PDR, offering promising directions for further research and clinical interventions.

Investigative Ophthalmology & Visual ScienceVol. 65(13)
Nankai University (CN), Tianjin Medical University General Hospital (CN), Tianjin Medical University (CN)
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 21%
Retinal Development and Disorders
1.17
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