PINK1/Parkin-Mediated Mitophagy Ameliorates Mitochondrial Dysfunction in Lacrimal Gland Acinar Cells During Aging
Overall, our findings suggested that aging could impair mitochondrial function of acinar cells, and age-related alterations may be treated with therapeutic approaches that enhance mitophagy while maintaining mitochondrial function.
Authors
- Yujie Ren (ORCID: https://orcid.org/0000-0002-8467-6766)
- Wanpeng Wang (ORCID: https://orcid.org/0000-0002-4201-895X)
- Han Zhao (ORCID: https://orcid.org/0000-0002-9920-5908)
- Yue Zhang (ORCID: https://orcid.org/0000-0002-7786-0231)
Institutions
- Central South University (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
- Second Xiangya Hospital of Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1167/iovs.65.13.12
- Citations
- 15
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 5.80