The interplay between spirometric inspiratory measurements and asthma control

<bold>Introduction:</bold> The management of asthma poses a continual challenge in healthcare, necessitating a nuanced understanding of respiratory function parameters particularly inspiratory measurments and their association with disease control. <bold>Methods:</bold> This retrospective study included 144 asthmatic patients who were referred to our department from 2020 to 2023. The degree of asthma control was gauged by the Asthma Control Questionnaire (ACQ). Spirometry was performed for all study population with measurement of Forced Expiratory Volume in one second (FEV1 in L), Forced Vital Capacity (FVC in L), FEV1/FVC ratio , Peak Expiratory Flow (PEF in L) , PIF (L), FIVC (L) and FIV (L). <bold>Results:</bold> Mean age was 44.288±17.61 years with a considerate female predominance (65.3%). Asthma was controlled in 69% of cases and spirometry was normal among 61.5% of our patients. Means of FEV1(L), FVC(L), FEV1/FVC ratio were 2.43±0.83, 3.25±1.09 and 75.1±10.83 , respectively. As for inspiratory measurements, means of PIF, FIVC and FIV were 3.52±1.42, 2.66±0.98 and 2.43±0.97, respectively. The ACQ score was negatively correlated with FEV1(P<0.05; r=-0.221), PEF (P<0.05; r=-0.216) and PIF (P<0.05; r=-0.276). However, there was no significant correlations between asthma control assessed by ACQ questionnaire and the FVC, FIVC and FIV. <bold>Conclusion:</bold> A comparable correlation was found between PIF and ACQ as well as FEV1 and ACQ which underscore the clinical relevance of PIF a potential indicator of disease control.